Gordon G. Hammes

University Distinguished Service Professor of Biochemistry, Emeritus

Single molecule fluorescence studies of enzyme mechanisms and protein dynamics

Contact Information

Mailing Address

Education

• B A (Princeton University, 1956)

• Ph.D. (University of Wisconsin, 1959)

Research Interests

My research interests are in the field of enzyme mechanisms, especially the application of thermodynamics and kinetics for the elucidation of mechanism. Recent work has utilized transient kinetics and single molecule fluorescence microscopy to probe the molecular mechanisms of enzyme catalysis.

Recent Publications

1. Stephen J. Benkovic, Gordon G. Hammes, and Sharon Hammes-Schiffer, “Free Energy Landscape of Enzyme Reactions”, Biochemistry 47, 3317-3321 (2008). More…

2. R. D. Smiley, T. R. L. Collins, G. G. Hammes, and T. Hsieh, “Single Molecule Measurements of the Opening and Closing of the DNA Gate by Eukaryotic Topoisomerase II”, Proc. Natl. Acad. Sci. USA 107, 4840-4845 (2007). More…

3. Gordon G. Hammes, Physical Chemistry for the Biological Sciences, John Wiley and Sons, Inc., 2007. More…

4. R. D. Smiley and G. G. Hammes, “Single Molecule Studies of Enzyme Mechanisms”, Chem. Rev. 45, 3080-3094 (2006). More…